Background: Parkinsonââ?¬â?¢s disease (PD) is the second commonest neurodegenerative disease in developed countries.\nCurrent treatment for PD is pharmacologically focused and can have significant side-effects. There is increasing\ninterest in holistic approaches including mindfulness to help manage the challenges associated with living with\nPD. We hypothesised that there would be an improvement in PD associated function and wellbeing in participants\nafter participating in a 6-week mindfulness-based lifestyle program, and that these improvements would be sustainable\nat 6 months. Our primary objective was to determine changes in function and wellbeing associated with PD.\nMethods: An exploratory prospective, mixed-method, randomised control trial incorporating a before and after design\nwith a waitlist control, with an embedded qualitative component was conducted in 2012ââ?¬â??2013. Participants included\ncommunity living adults with disability congruent to H&Y Stage 2 PD, aged 18ââ?¬â??75, fluent in spoken and written\nEnglish and able to attend at least four of six sessions of the program. Participants were randomised to the\nintervention or wait-list control groups at two locations. All participants in the wait-list control group eventually\nreceived the intervention. Two randomisation codes were created for each location. Allocation to the intervention or\nwait-list control was by random number generation. The program facilitator and participants were blinded to\nparticipant data.\nResults: Group 1 included 35 participants and group 2 (the waitlist control), 37. Data was analysed from 24\n(group 1) and 33 (group 2) participants. The intervention group, compared to the waitlist control, showed a\nsmall improvement in function and wellbeing associated with PD immediately after the program (t-score = âË?â??0.\n59) and at 6-month post intervention (t-score = âË?â??1.42) as reported by the PDQ-39 SI. However this finding\nwas not significant (p = 0.56 and 0.16 respectively). A small yet significant effect size (Ã?² = 0.23) in PDQ-39 ADL\nwas reported in group 1 after 6-months post-intervention. This showed a positive improvement in the ADL as\nreported by group 1 after 6-months (t-score âË?â??1.8, p = 0.04). Four secondary measures are reported. Conclusions: Our findings suggest mindfulness-based lifestyle programs have potential to assist participants in\nmanaging the ongoing difficulties associated with a neurological condition such as Parkinsonââ?¬â?¢s disease. Importantly,\nour study shows promise for the long term benefits of such programs. Improvements to participant activities in daily\nliving and mindfulness were retained at 6-months post intervention. A more definitive study should be conducted in\na larger sample of PD patients to further explore these findings and their impact on reducing stress and anxiety\nin PD patients.
Loading....